Compound Deep-Dives: Bioregulators & Gut Peptides
This section collects detailed, single-compound profiles for peptide bioregulators and gut-health agents that sit outside the main research library. Each page covers what the compound is, its proposed mechanism, the state of the published research, and practical considerations — with sources, not hype.
The compounds here fall into two broad groups:
- Peptide bioregulators (short Khavinson-style peptides studied largely in Russian literature) — Cartalax, Sigumir, Thymagen, and Vladonix.
- Gut & barrier-health compounds — Larazotide (a zonulin/tight-junction modulator), Tributyrin (a butyrate prodrug), Zinc-L-Carnosine, and PEA (palmitoylethanolamide).
Profiles are educational only and not medical advice. Where clinical evidence is thin or early-stage, we say so plainly. For the broader picture on this class, see the Bioregulators Guide and the Gut Healing Stack.
Cartalax: Advanced Cartilage Bioregulator Peptide
Complete guide to Cartalax peptide - a bioregulator for cartilage and connective tissue repair. Research, dosing, and comparison to similar compounds.
Larazotide: Tight Junction Peptide for Gut Permeability
Complete guide to Larazotide (AT-1001) - the zonulin antagonist for intestinal permeability. Mechanism, research status, and practical considerations.
PEA (Palmitoylethanolamide): The Endogenous Pain & Inflammation Compound
Complete guide to PEA - the fatty acid amide for pain, inflammation, and neuroprotection. Mechanism, dosing, research status, and practical use.
Sigumir: The Cartilage & Joint Peptide
Complete guide to Sigumir - a bioregulator peptide for cartilage and joint health. Mechanism, dosing, research, and practical use.
Thymagen: Thymus Bioregulator for Immune Support
Complete guide to Thymagen - the thymus peptide bioregulator. Immune function, aging, dosing protocols and what the research shows.
Tributyrin: The Stable Butyrate for Gut Health
Complete guide to Tributyrin - the pro-drug form of butyrate for intestinal health. Why it's better than sodium butyrate, dosing, and practical use.
Vladonix: Thymus Extract Bioregulator for Immune Support
Complete guide to Vladonix - the natural thymus peptide extract. Immune function, comparison to synthetic alternatives, and practical use.
Zinc L-Carnosine: The Gut Healing Mineral-Peptide Complex
Complete guide to Zinc L-Carnosine (Polaprezinc) - the chelated zinc compound for gut health, ulcers, and stomach protection.